Brand Name Manufacturers
Depo-Estradiol by Pharmacia/Upjohn
Depogen by Hyrex
Dep-gynogen by Forest
Estro-cyp by Keene
Ester with estradiol same effect as endogenous estrogen
Sustained release intramuscular injection,
Approved by U.S. FDA
Estrogen replacement therapy in females
Active blood clotting disorders. Estrogen-dependent tumors. History of blood clotting disorders associated with estrogen use. History of sensitivity to estradiol or any part of the preparation. Known or suspected breast cancer except in appropriately selected patients.
Convulsions. Dizziness. Headache. Migraine. Mental depression. Spasms of limb and facial muscles.
Intolerance to contact lenses. Steepening of corneal curvature.
Abdominal cramps. Bloating. Cholestatic jaundice. Nausea. Vomiting.
Blotchy skin pigmentation. Localized skin irritation. Loss of scalp hair. Increase of body hair. Red skin patches from capillary congestion.
Blood clotting disorders. Elevated blood pressure. Fluid retention. Glucose intolerance. Increased serum calcium level. Increased sensitivity to light. Liver tumors.