Depo Lupron The drug can be injected into a muscle or under the skin once a month or every 3 months. It also can be injected daily under the skin. The long-acting form of leuprolide (given once a month or every 3 months) is slowly released into the bloodstream during that period.
This medication is used to treat:     This medication is sometimes prescribed for other uses; ask your doctor or pharmacist for more information.
    Leuprolide is in a class of drugs known as gonadotropin-releasing (LH-RH) hormone analogs. It stops the production of testosterone in men and estrogen in females. Blocking the production of these hormones is desirable because they stimulate the growth of the diseased cells involved in prostate cancer and endometriosis. When the medication is stopped, these hormone levels return to normal.

Before taking leuprolide,
You should know that leuprolide may interfere with the normal menstrual cycle (period) in women and may stop sperm production in men. Amenorrhea (stopping of the monthly menstrual cycle) and vaginal discharge or bleeding may occur with leuprolide therapy. This effect occurs in women who receive 10 weeks or more of therapy and have not been through menopause. However, you should not assume that you cannot get pregnant or that you cannot get someone else pregnant. Women who are pregnant or breast-feeding should tell their doctors before they begin taking this drug. You should not plan to have children while receiving hormone therapy or for a while after treatments. (Talk to your doctor for further details.) Use a reliable method of birth control to prevent pregnancy. Leuprolide may harm the fetus.

Side effects
Although side effects from leuprolide are not common, they can occur. Tell your doctor if any of these symptoms are severe or do not go away: If you experience any of the following symptoms, call your doctor immediately:     Keep leuprolide in the container it came in and out of reach of children. Store it at room temperature and away from direct sunlight, excess heat and moisture (not in the bathroom). Do not allow leuprolide to freeze. Throw away any medication that is outdated or no longer needed. Talk to your pharmacist about the proper disposal of your medication.

In case of emergency/overdose
    In case of overdose, call your local poison control center at 1-800-222-1222. If the victim has collapsed or is not breathing, call local emergency services at 911.

Special instructions
In men, leuprolide may cause increased bone pain and increased difficulty in urinating during the first few weeks of treatment. These effects may result from an initial increase in testosterone. Notify your doctor should this occur. Continue to take leuprolide even if you feel well. Do not stop taking leuprolide without talking to your doctor.
Last Revised - 01/01/2003