Malone, Maoileoin A Gaelic surname meaning descendant of devotee of St. John. An ecclesiastical sept of Clonmacnoise. In 1890 Malone was principally found in Dublin, Wexford and Clare, and the estimated number of bearers was 4,480. In the United States Malone is the 397th most numerous surname with an estimated 77,000 bearers.