LUCIEN BRULL
(1898 – 1959)
(Extracts from this appreciation appeared in The Times, Nov 2nd, 1959;
The Lancet, Nov 7th, 1959 and the British Medical journal, Dec 12th, 1959.
By the sudden death of Dr. Lucien Brüll, Professor of Clinical
Medicine in the University or Liège, Belgian medical and scientific
circles have lost a much beloved physician, an enthusiastic research worker
and a wise counselor. And his many friends in this country, to which he was
deeply attached, as well as in other European countries and in the United
States, will sadly miss that kindness or heart, abounding generosity, sparkling
wit (often satirical but never malicious) and that fondness for good living
which, together, made him so lovable.
Born in 1898 Lucien Brull spent his boyhood in Tongres and acquired
a lasting affection for the Campine countryside where, some fifty miles
to the north of Liège, his father owned a large estate of forest
and agricultural land which Lucien Brüll later inherited. He completed
his medical training at the University of Liège; obtaining its Doctorate
of Medicine in 1924 with the highest distinction.
It was then that Queen Elizabeth of the Belgians, whose constant interest
and help in promoting research in the medical sciences will always be
remembered with gratitude, was visiting Professor Starling's laboratory
at University College, London, where under his inspiration and guidance,
an enthusiastic group of young scientists were learning the disciplines
of physiological research. When the Queen commented on the absence of any
Belgian workers it was suggested that her influence be used, and it was
not long afterwards that Lucien Brüll came to University College as
Lauréat du Concours des Bourses de Voyages. He thus in his youth
gained an international outlook for his career and quickly made life-long
friendships. This power to give and take friendship had the most fruitful
results not only for his personal work but also for British and European
physiology and medicine. Throughout his research life he frequently referred
to the debt he owed Starling in shaping his outlook and future career. Indeed,
it was this experience in England and that of the following year in Strasbourg
where, under Professors Nicloux and Terroine, he studied the techniques of
physiological chemistry, which convinced Lucien Brüll that advances
in medicine depend upon the application of physiological methods to its problems,
and that the university role of the clinician is one which cannot but absorb
his whole time and energy. Thus he became the first full-time University
clinician in Belgium; and in 1937 the University of Liège built, to
his design and in structural connection with his wards, the Research Institute
which will remain as the tangible expression of his outlook and aims. The
organization and financing of this Institute were unique and original in
that Lucien Brüll made its staffing, equipment and maintenance self-supporting
through a fund dispensed by the University and secured by fees from private
patients and contributions from social insurance agencies. Here were accommodated
not only his staff of fulltime physicians and medical scientists but many
visitors from abroad who were eager, under Lucien Brülls guidance, to
unravel the biological processes underlying physiological and pathological
phenomena in man and the lower animals. In addition some thirty technicians
were employed in the multifarious and routine analyses associated with modern
clinical investigation.
And in spite of the exacting teaching and administrative duties of
his office - he was fearless, eloquent and effective on committee and
in debate - Lucien Brüll continued throughout his career to work
in an individual capacity on problems in the field of his special interests,
a fact that contributed so much to the vitality and enthusiasm with which
his younger associates were infected. Although his research institute was
divided into departments each specializing in the disciplines needed for
advancement in a particular field of medical knowledge, and each under the
direction of a senior member of his staff, the institute, his wards and his
clinics formed an autonomous whole. Every morning at eight o'clock he presided
at a brief conference with his staff. He realized the dangers of specialized
research divorced from the tempering and nourishing experience of general
medicine; and he insisted that all his medical staff, senior and junior
alike, should take their full share of responsibility in the wards and outpatient
clinics. He was thus, too, paying a silent tribute to the essential nature
of the work of the general practitioner.
The modesty and self-effacement inherent in Licien Brüll’s character
– honors, offices and responsibilities in national and academic circles
were willy-nilly thrust upon him - have largely obscured the real and important
part he has played in the advancement of medical science. It is fitting,
therefore, briefly to mention a few of his achievements. He was the first
to demonstrate experimentally the temporary cure of uraemia by kidney grafts,
and to elaborate a "mechanical heart" whereby organs could be perfused,
and their function maintained, with oxygenated blood free from anticoagulants.
Many of the difficulties encountered in the advancing front of human cardiovascular
surgery derive from the inescapable contact of blood with foreign surfaces,
and it may well be that the principle of Lucien Brüll's fundamental
work in the field of viviperfusion will later find fruitful application
to human needs. Further, he was one of the first to utilize radioactive
isotopes in biological research and therapeutics, and the first on the continent
to introduce radioactive iodine in the treatment of thyrotoxicosis. His
goitre clinic quickly became one of the world's most active centers for
the assessment and treatment of thyroid disease. It is, too, of interest
to recall that he established the first "blood-bank" in Belgium with the
collaboration of Professor Moureau who, through this transfusion service,
discovered the Rh factor at the same time as his American colleagues. His
organizing ability is further shown in his outstanding contribution that
he, in his later years, made to the development of Gerontology, work that
culminated in his founding the International Association and presiding in
Liège at its first congress.
Nor was this all. Lucien loved the countryside and, whenever his academic
responsibilities allowed, he and his wife, often accompanied at weekends
by relations and close friends, would seek the retreat of their estate
in Campine, part of which they had recently enclosed as a bird sanctuary.
During the last world war, and after their temporary separation at
the time of the German invasion, they frequently cycled to and from their
estate, bringing back farm produce to the sick and needy families in the
hospital. The responsibility for this estate had given Lucien Brüll
such intimate knowledge of forestry and agriculture that at the behest
of the Belgian Government and as Director of the Mission Interdisciplinaire
de l'Université de Liége au Katanga, he has made, since the
war, many trips to the Congo not only to plan clinics, schools and craft
centers, but also to advise the local administration on the pressing problems
of land clearance and crop cultivation by the native population. He envisaged
the creation of experimental native villages and had the satisfaction on
his last visit of seeing the first of these in full and happy operation in
Haut Katanga: it is to be named after him. Thus as an agronomist no less
than as a physician he has played an outstanding role in colonial development
in Africa. It was his firm conviction that in patient education and the supply
of technicians with a vocation to serve lay the road to civilizing primitive
peoples. He had a horror of dangers and crudities which over-rapid commercial
exploitation so often exhibits, and vigorously opposed land ownership by
the governing nation.
Some, his students among them, will remember Lucien Brüll for
the clarity and simplicity of his expositions, others for his vivacity
and power of quick decision, others for his understanding of and sympathy
with nature in all her aspects and problems, yet others for his wit and
bonhomie: all will remember him for his integrity, disinterestedness, high
social purpose and his immense qualities of heart and spirit. He died on
the ninth of September in the calm retreat of his charming home at Houlpays
overlooking the Meuse valley and where he and his wife had adored to be
surrounded by those whom they loved; and he is buried, as was his wish,
in the little cemetery nearby, without the least mark to distinguish him
from the country folk of the neighboring villages. His memorial is secure
in the hearts and minds of the many that knew and loved him.
E.B. VERNEY.
|